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Rectal Cancer treatment details. Chemotherapy. Infermi Hospital, Rimini, Italy

Survival: 14.0 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Adrucil
Country: Italy
City/State/Province: Rimini
Hospital: Infermi Hospital
Journal: Link
Date: 5/2002

Patients: This Phase II trial, involved 45 patients with metastatic colorectal cancer. Most patients (62%) had only one metastatic site.

Treatment: Treatment consisted of the bolus administration of there chemotherapy drugs Fluorouracil (5-FU, adrucil), Leucovorin, and Oxaliplatin (eloxatin).

Toxicity: Toxicities included grade 3 or 4 diarrhea and neutropenia. Four patients were withdrawn from the study because of toxicity that was probably related to treatment. Other toxicities included: thrombocytopenia, anemia, infection, nausea, vomiting, mucositis, cutaneous, alopecia, and neurologic toxicity.

Results: Median survival was 14 months.

Correspondence: Alberto Ravaioli, MD

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