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Prostate Cancer treatment details. Biologic therapy. Massachusetts General Hospital Cancer Center, Boston, MA, United States



Survival: 37.9 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Boston, MA
   
Hospital: Massachusetts General Hospital Cancer Center
   
Journal: Link
   
Date: 4/2014

Description:
Patients:
This phase 3 study involved 323 castration- resistant prostate cancer patients with bone metastases and a median age of 66.1 years.

Treatment:
Patients received zoledronic acid, a biologic therapy agent that inhibits breakdown of bone.

Toxicities:
There was one treatment-related death due to kidney failure. Grade 3 pain and fatigue were also reported.

Results:
The median overall survival was 37.9 months.

Support:
This study was partially supported by Novartis Oncology.

Correspondence: Dr. Matthew R. Smith; email: smith.matthew@mgh.harvard.edu

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