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Prostate Cancer treatment details. Chemotherapy. Hormone. Changhai Hospital, Shanghai , China



Survival: 13.6 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Hormone
   
Drugs:
Country: China
   
City/State/Province: Shanghai 
   
Hospital: Changhai Hospital
   
Journal: Link
   
Date: 1/2015

Description:
Patients:
This study involved metastatic castration-resistant patients who were divided into two separate treatment groups. Group A consisted of 113 patients with a median age of 70.7 years. Group B had 115 patients with a median age of 70.8 years.

Treatment:
Patients in group A received chemotherapy with docetaxel and hormone therapy with prednisone.

Patients in group B received chemotherapy with mitoxantrone and hormone therapy with prednisone.

Toxicities:
There were three treatment-related deaths in group A due to unspecified causes. Grade 3-5 neutropenia, leukopenia, alopecia, and infection were reported.

There were two treatment-related deaths in group B due to unspecified causes. Grade 3-5 neutropenia, leukopenia, and infection were reported.

Results:
The median overall survival for groups A and B was 21.88 and 13.67 months, respectively.

Support:
This study was supported by Sanofi-Aventis.

Correspondence: Dr. Ying-hao Sun; email: yinghao.sun@yahoo.com

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