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Breast Cancer treatment details. Chemotherapy. Peking Union Medical College, Beijing, China



Survival: 35.3 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: China
   
City/State/Province: Beijing
   
Hospital: Peking Union Medical College
   
Journal: Link
   
Date: 6/2015

Description:
Patients:
This phase 3 study involved female advanced metastatic breast cancer patients who were divided into two separate treatment groups. Group A consisted of 104 patients with a median age of 52 years. Group B had 102 patients with a median age of 52 years.

Treatment:
Patients in group A received chemotherapy with docetaxel and capecitabine.

Patients in group B received chemotherapy with vinorelbine and capecitabine.

Toxicities:
The most severe toxicities in group A were of grade 4 and included neutropenia and liver toxicity. Grade 3 hand-foot syndrome and gastrointestinal reactions were also reported.

The most severe toxicities in group B were of grade 4 and included neutropenia and liver toxicity. Grade 3 hand-foot syndrome and leukopenia were also reported.

Results:
The median overall survival times for groups A and B were 35.3 and 19.8 months, respectively.

Support:
This study was supported by Shanghai Roche Pharmaceuticals Ltd.

Correspondence: Dr. Binghe Xu; email: xubinghebm@163.com

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