Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results

Click here to go back to your search results.

Liver Cancer treatment details. Biologic therapy. Massachusetts General Hospital Cancer Center, Boston, MA, United States

Survival: 9.2 months
Toxicity Grade: 5
Treatments: Biologic therapy
Country: United States
City/State/Province: Boston, MA
Hospital: Massachusetts General Hospital Cancer Center
Journal: Link
Date: 7/2015

This phase 3 study involved 283 advanced hepatocellular carcinoma patients who were previously treated with sorafenib. The median patient age was 64 years and 83% were male.

Patients received biologic therapy with ramucirumab, a monoclonal antibody specific to the VEGFR-2 that inhibits cancer cell growth.

Treatment-related deaths due to respiratory distress, kidney failure, and bleeding/hemorrhage were reported. Grade 4 decreased appetite and grade 3 high blood pressure were also reported.

The median overall survival was 9.2 months.

This study was supported by Eli Lilly and Co.

Correspondence: Dr. Andrew X Zhu; email:

E-mail to a Friend Email Physician More Information