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Ovarian Cancer treatment details. Biologic therapy. Princess Margaret Cancer Centre , Toronto, Canada



Survival: 18.9 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: Canada
   
City/State/Province: Toronto
   
Hospital: Princess Margaret Cancer Centre
   
Journal: Link
   
Date: 7/2015

Description:
Patients:
This phase 2 study involved 74 recurrent ovarian, peritoneal, or fallopian tube cancer patients who had received prior platinum-based chemotherapy. The median patient age was 58 years.

Treatment:
Patients received biologic therapy with cediranib, an inhibitor of the VEGFR protein that interferes with cancer cell growth.

Toxicities:
There was one treatment-related death due to brain hemorrhage. Grade 3 fatigue and grade 4 high blood pressure were also reported.

Results:
The median overall survival was 18.9 months.

Correspondence: Dr. A.M. Oza; email: amit.oza@uhn.ca

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