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Ovarian Cancer treatment details. Biologic therapy. Princess Margaret Cancer Centre , Toronto, Canada

Survival: 18.9 months
Toxicity Grade: 5
Treatments: Biologic therapy
Country: Canada
City/State/Province: Toronto
Hospital: Princess Margaret Cancer Centre
Journal: Link
Date: 7/2015

This phase 2 study involved 74 recurrent ovarian, peritoneal, or fallopian tube cancer patients who had received prior platinum-based chemotherapy. The median patient age was 58 years.

Patients received biologic therapy with cediranib, an inhibitor of the VEGFR protein that interferes with cancer cell growth.

There was one treatment-related death due to brain hemorrhage. Grade 3 fatigue and grade 4 high blood pressure were also reported.

The median overall survival was 18.9 months.

Correspondence: Dr. A.M. Oza; email:

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