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Melanoma treatment details. Immunotherapy. Churchill Hospital, Oxford, United Kingdom



Survival: 41.5 months
   
Toxicity Grade: 4
   
Treatments: Immunotherapy
   
Drugs:
Country: United Kingdom
   
City/State/Province: Oxford
   
Hospital: Churchill Hospital
   
Journal: Link
   
Date: 1/2014

Description:
Patients:
This phase 2 study involved 96 melanoma patients with a median age of 53 years and 47.9% male.

Treatment:
Patients received immunotherapy with interferon-alpha 2b (IFN-a-2b), which stimulates the immune system to attack cancer cells.

Toxicities:
The most severe toxicities were of grade 4 and included neutropenia, liver toxicity, and fatigue. Grade 1-2 vomiting and nausea were also reported.

Results:
The median overall survival was 41.5 months.

Support:
Some of the study’s authors have advisory and/or financial relationships with several pharmaceutical companies.

Correspondence: Dr. Mark R. Middleton; email: Mark.Middleton@oncology.ox.ac.uk

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