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Rectal Cancer treatment details. Chemotherapy. The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States



Survival: 12.8 months
   
Toxicity Grade: 3
   
Treatments: Chemotherapy
   
Drugs: Xeloda
Country: United States
   
City/State/Province: Houston, Texas
   
Hospital: The University of Texas M.D. Anderson Cancer Center
   
Journal: Link
   
Date: 6/2004

Description:
Patients: This Phase II study involved 22 patients with metastatic colorectal cancer. All patients had been previously treated with 5-FU.

Treatment: Treatment consisted of the chemotherapy drug, capecitabine (xeloda).

Toxicity: Grade 3 toxicities included: hand-foot syndrome, diarrhea, fatigue, nausea, mucosal inflammation, abdominal pain, vomiting, and chest pain.

Results: No objective responses were observed. Median time to disesse progression was 64 days. Median survival time was 12.8 months.

Support: This study was supported in part by Hoffman-La Roche. Three of the studies authors receive funding from Roche Labs. Hoffman-La Roche markets capecitabine.

Correspondence: Paulo M. Hoff, MD

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