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Brain Cancer treatment details. Biologic therapy. Drexel University College of Medicine, Pennsylvania , United States

Survival: 13.4 months
Toxicity Grade:
Treatments: Biologic therapy
Country: United States
City/State/Province: Pennsylvania
Hospital: Drexel University College of Medicine
Journal: Link
Date: 1/2002

Patients: This Phase II study involved 180 patients with high grade glioma. The patient population consisted of 118 patients with glioblastoma multiforme, 55 with anaplastic astrocytoma foci, 2 with oligodendromas, and 5 undetermined (“unconfirmed pathological characteristics”). All patients had received prior surgery and radiation therapy, with or without chemotherapy.

Treatment: Treatment consisted of radio-labeled MAb 425 (radioiodinated monoclonal antibody).

Toxicity: No acute or chronic toxicities noted except for hypothyroidism in one glioblastoma patient.

Results: For patients with glioblastoma multiforme, the overall median survival was 13.4 months.

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