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Breast Cancer treatment details. Chemotherapy. Churchill Hospital, Oxford, United Kingdom



Survival: 7.6 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Xeloda
Country: United Kingdom
   
City/State/Province: Oxford
   
Hospital: Churchill Hospital
   
Journal: Link
   
Date: 5/2002

Description:
Patients: This Phase II study involved 44 women with advanced and/or metastatic breast cancer. Most patients had been treated previously with other regimens. Patients were divided into two groups 22 in Group A and 20 in Group B. (Two patients were part of a third group that was discontinued.)

Treatment: Patients in group A were administered the oral drug capecitabine (xeloda). Patients in group B were treated with the drug paclitaxel (intravenous).

Toxicity: In group A, there was grade 3-4 neutropenia. Other toxicities included: nausea, diarrhea, vomiting, fatigue, stomatitis, pyrexia, and hand-foot syndrome.

Results: Median survival was 7.6 months for patients in group A.

Support: This study was sponsored by F. Hoffmann-La Roche. Roche markets xeloda.

Correspondence: D. Talbot, MD

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