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Breast Cancer treatment details. Chemotherapy. British Columbia Cancer Agency-Vancouver Cancer Center, Vancouver, British Columbia, Canada



Survival: ?
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: Canada
   
City/State/Province: Vancouver, British Columbia
   
Hospital: British Columbia Cancer Agency-Vancouver Cancer Center
   
Journal: Link
   
Date: 4/2003

Description:
Patients: This Phase II study involved 33 women with advanced or metastatic breast cancer.

Treatment: The treatment consisted of administration of a new chemotherapy drug called ZD0473 (a new generation platinum compound).

Toxicity: Hematological toxicity was significant (grade 1-4). Other toxicities included: fever, fatigue, anorexia, nausea, vomiting, stomatitis, taste disturbance, constipation, diarrhea, hemorrahage, neuro/sensory, neuro/motor, blurred vision, flashing lights, auditory/hearing, headache, myalgia, alopecia, rash, dry skin, dyspnea, cough, palpitations, and petechiae/purpura.

Results: There is one partial response in one patient. Overall survival was not discussed.

Support: This trial was supported by a grant from AstraZeneca.

Correspondence: Dr. K.A. Gelmon

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