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Brain Cancer treatment details. Chemotherapy. Radiation. University of Marburg, Marburg, Germany



Survival: 15.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Radiation
   
Drugs: Hycamtin
Country: Germany
   
City/State/Province: Marburg
   
Hospital: University of Marburg
   
Journal: Link
   
Date: 12/2001

Description:
Patients: This study involved 60 patients with glioblastoma multiforme. The average age of the patients was 57.

Treatment: Treatment consisted of simultaneous chemotherapy and radiotherapy following surgery. The chemotherapy drug was topotecan (Hycamtin).

Toxicity: Two patients died of infectious complications while undergoing therapy. Other toxicities included hematologic (grade 1-3), nausea (grade 1-3), mucositis (grades 2,4), headache (grade1-2), tremor (grade 1-2), consciousness (grades 1-2, 4), and motor functions (grade 1-4).

Results: The median survival was 15 months.

Correspondence: M.W. Gross, MD

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