Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Mesothelioma Cancer treatment details. Biologic therapy. Chemotherapy. The Royal Marsden Hospital, Sutton, United Kingdom



Survival: 10.5 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs: Mitozytrex
Platinol
Country: United Kingdom
   
City/State/Province: Sutton
   
Hospital: The Royal Marsden Hospital
   
Journal: Link
   
Date: 2/2002

Description:
Patients: This Phase I study involved 13 patients with malignant mesothelioma.

Treatment: The treatment consisted of a suspension of heat-killed Mycobacterium vaccae (SRL172), a fast growing avirulent mycobacterium, that may have non-specific immunomodulating properties in combination with standard chemotherapy (mitomycin-C (mitozytrex), vinblastine (velban) and cisplatin (platinol)).

Toxicity: Grade 1-3 toxicities included infection, emesis, mucositis, diarrhea, constipation, alopecia, neuropathy, fatigue, and hematological.

Results: The median overall survival was 10.5 months.

Support: This study was supported by a research grant from SR Pharma. SR Pharma markets SRL172.

Correspondence: MER O’Brien, MD

E-mail to a Friend Email Physician More Information