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Mesothelioma Cancer treatment details. Chemotherapy. Immunotherapy. Center Hospitalier Intercommunal de Creteil, Creteil, France



Survival: 29.2 months
   
Toxicity Grade: 3
   
Treatments: Chemotherapy
Immunotherapy
   
Drugs: Mitozytrex
Platinol
Country: France
   
City/State/Province: Creteil
   
Hospital: Center Hospitalier Intercommunal de Creteil
   
Journal: Link
   
Date: 6/2002

Description:
Patients: This Phase II study involved 17 patients with Malignant Pleural Mesothelioma. Many of the patients had undergone “preventive radiotherapy.”

Treatment: The treatment consisted of a type of immunotherapy – administration of intrapleurally infused autologous human activated macrophages (a type of blood cell) followed by intrapleural injection of gamma-interferon (a type of protein). After completion of this therapy, ten patients were treated with chemotherapy (primarily cisplatin (platinol) and mitomycin (mitozytrex)).

Toxicity: Toxicities included grade 2 or 3 thoracic pain after injection, fever, and alkaline phosphatases.

Results: The median survival of all treated patients was 29.2 months.

Correspondence: Manuel Lopez, MD

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