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Lung Cancer treatment details. Chemotherapy. Helen F. Graham Cancer Center, Wilmington, Delaware, United States

Survival: 8.8 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Gemzar
Country: United States
City/State/Province: Wilmington, Delaware
Hospital: Helen F. Graham Cancer Center
Journal: Link
Date: 9/2002

Patients: This Phase I study involved 30 patients with inoperable advanced (stage IIIB or IV) non-small cell lung cancer. No patients had been administered prior chemotherapy.

Treatment: Treatment consisted of administration of three drugs, topotecan (hycamtin), cisplatin (platinol), and gemcitabine (gemzar).

Toxicity: Toxicity included hematological (grade 3-4) and alopecia.

Results: Median overall survival was 38 weeks (8.8 months).

Support: The study was supported by GlaxoSmithKline and one of the study’s authors is associated with GlaxoSmithKline.

Correspondence: Michael J. Giarino, MD

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