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Lung Cancer treatment details. Chemotherapy. Helen F. Graham Cancer Center, Wilmington, Delaware, United States



Survival: 8.8 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Gemzar
Hycamtin
Platinol
Country: United States
   
City/State/Province: Wilmington, Delaware
   
Hospital: Helen F. Graham Cancer Center
   
Journal: Link
   
Date: 9/2002

Description:
Patients: This Phase I study involved 30 patients with inoperable advanced (stage IIIB or IV) non-small cell lung cancer. No patients had been administered prior chemotherapy.

Treatment: Treatment consisted of administration of three drugs, topotecan (hycamtin), cisplatin (platinol), and gemcitabine (gemzar).

Toxicity: Toxicity included hematological (grade 3-4) and alopecia.

Results: Median overall survival was 38 weeks (8.8 months).

Support: The study was supported by GlaxoSmithKline and one of the study’s authors is associated with GlaxoSmithKline.

Correspondence: Michael J. Giarino, MD

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