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Brain Cancer treatment details. Chemotherapy. Radiation. Fox Chase Cancer Center, , Philidelphia, Pennsylvania, United States



Survival: 9.7 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Radiation
   
Drugs: Taxol
Country: United States
   
City/State/Province: Philidelphia, Pennsylvania
   
Hospital: Fox Chase Cancer Center,
   
Journal: Link
   
Date: 9/2001

Description:
Patients: This Phase II study involved 62 patients with supratentorial glioblastoma multiforme. One patient was removed after refusing protocol treatment.

Treatment: Treatment consisted of a chemotherapy drug, paclitaxel (taxol) and conventional external beam radiation therapy.

Toxicity: Toxicities included grade 1-4 nausea/vomiting, grade 1-2 diarhhea, grade 1-2 mucosistis, grade 3-4 allergy, grade 1-2 neutropenia, grade 1-2 thrombocytopenia, and grade 1-4 neurotoxicity.

Results: With median potential follow-up of 20 months, actual median survival was 9.7 months.

Correspondence: Dr. C.J. Langer

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