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Lung Cancer treatment details. Chemotherapy. Hospital Germans Trias I Pujol Hospital, Badalona, Spain

Survival: 9.8 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Platinol
Country: Spain
City/State/Province: Badalona
Hospital: Hospital Germans Trias I Pujol Hospital
Journal: Link
Date: 10/2002

Patients: This Phase III study involved 608 patients with advanced (stage IIIB or IV) non-small-cell lung cancer. Patients were divided into two groups. Group A contained 302 patients and Group B contained 306 patients.

Treatment: For patients in Group A, the treatment consisted of two drugs – paclitaxel (taxol) and cisplatin (platinol). In addition, 45% of patients received follow-up radiotherapy and 23% received another chemotherapy regimen.

Toxicity: Grade 3-4 toxicities in Group A included hematological, infections, and peripheral neuropathy. Other toxicities included arthralgia/myalgia, asthenia, ototoxicity, nausea/vomiting, diarrhea, and renal toxicity.

Results: Median survival was 9.8 months for patients in Group A.

Support: This study was supported by Bristol-Myers Squibb. In addition, two of the study’s authors are affiliated with Bristol-Myers Squibb.

Correspondence: Dr. R. Rosell

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