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Lung Cancer treatment details. Chemotherapy. Hospital Central de Asturias, Oviedo, Spain

Survival: 11.0 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Gemzar
Country: Spain
City/State/Province: Oviedo
Hospital: Hospital Central de Asturias
Journal: Link
Date: 8/2002

Patients: This Phase I/II study involved 65 patients with advanced (stage IIIA, IIIB, or IV) non-small cell lung cancer. None of the patients had received prior chemotherapy or radiotherapy.

Treatment: The treatment consisted of three drugs gemcitabine (gemzar), vinorelbine (navelbine), and cisplatin (platinol).

Toxicity: There was one toxic death (in the phase I period) from grade 4 netropenia associated with pneumonia. Other events included grade 1-4 hematologic toxicities, and grade 1-3 nausea/vomiting, alopecia, stomatitis, and hepatic.

Results: Overall median survival was 11 months.

Support: Eli Lilly and Company helped in data management for this study.

Correspondence: E. Esteban, MD

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