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Lung Cancer treatment details. Chemotherapy. Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy

Survival: 11.0 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Gemzar
Country: Italy
City/State/Province: Milan
Hospital: Istituto Nazionale per lo Studio e la Cura dei Tumori
Journal: Link
Date: 2/2003

Patients: This Phase II study involved 86 patients with stage IV non-small-cell lung cancer. None of the patients had prior chemotherapy.

Treatment: The treatment consisted of two drugs gemcitabine (gemzar) and carboplatin (paraplatin). (Patients were divided into 4 groups and each group received the two drugs in a slightly different order and/or with different intervals.)

Toxicity: Toxicities included grade 1-4 hematologic and allergic reactions, and grade 3 or less skin rashes, liver toxicity, fatigue, nausea/vomiting, alopecia, and flu-like symptoms.

Results: Median survival for each group ranged from 7-13 months and overall median survival was 11 months.

Correspondence: Dr. E. Bajetta

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