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Lung Cancer treatment details. Chemotherapy. Radiation. University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States



Survival: 24.0 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
Radiation
   
Drugs: Paraplatin
Taxol
Country: United States
   
City/State/Province: Chapel Hill, North Carolina
   
Hospital: University of North Carolina at Chapel Hill School of Medicine
   
Journal: Link
   
Date: 10/2002

Description:
Patients: This Phase I/II study involved 62 patients with stage IIIA (28 patients) or IIIB (34 patients) non-small-cell lung cancer. None of the patients had received prior chemotherapy or radiotherapy.

Treatment: Treatment consisted of chemotherapy, carboplatin (paraplatin) and paclitaxel (taxol) in combination with radiotherapy (high-dose conformal).

Toxicity: Toxicities included grade 4 hematologic, grade 3-4 esophagitis, and stage 3 malaise/fatigue.

Results: The median survival time was 24 months.

Support: The study was supported in part by a grant from Bristol-Meyers Squibb Corporation.

Correspondence: Julian Rosenman, MD

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