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Kidney Cancer treatment details. Immunotherapy. The Cleveland Clinic Foundation, Cleveland, Ohio, United States



Survival: 13.8 months
   
Toxicity Grade: 4
   
Treatments: Immunotherapy
   
Drugs:
Country: United States
   
City/State/Province: Cleveland, Ohio
   
Hospital: The Cleveland Clinic Foundation
   
Journal: Link
   
Date: 7/2004

Description:
Patients: This Phase I study involved 26 patients with metastatic renal cell carcinoma or malignant melanoma; nineteen men and seven women. The median age was 59. The majority of patients had received other therapies. Of the 26 patients, 19 had renal cell carcinoma.

Treatment: The treatment consisted of interleukin-12 and interferon alpha-2b.

Toxicity: Grade 3-4 toxicities included hematologic, elevated enzymes, fatigue, and fever.

Results: Median survival was 13.8 months.

Support: The study was supported by a grant from Schering-Plough and one of the authors had acted as a consultant for this company. Schering-Plough markets interferon alpha-2b.

Correspondence: Ronald M. Bukowski, MD

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