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Kidney Cancer treatment details. Chemotherapy. Memorial Sloan-Kettering Cancer Center, New York, New York, United States



Survival: N/R
   
Toxicity Grade: 3
   
Treatments: Chemotherapy
   
Drugs: Trisenox
Country: United States
   
City/State/Province: New York, New York
   
Hospital: Memorial Sloan-Kettering Cancer Center
   
Journal: Link
   
Date: 8/2002

Description:
Patients: This Phase II trial involved 14 patients with metastatic renal cell carcinoma, 7 men and 7 women. The median age was 55 and 8 had undergone prior nephrectomy.

Treatment: The treatment consisted of the administration of arsenic trioxide (Trisenox).

Toxicity: One patient died after the first cycle of arsenic trioxide. Cause of death was unknown and “felt unlikely due to arsenic trioxide.” Grade 3 toxicities included abdominal pain/cramping, and anemia. Other toxicities included renal insufficiency, diarrhea, dyspnea, rash, elevation in liver function tests, and hematologic toxicity.

Results: There were no complete or partial responses.

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