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Kidney Cancer treatment details. Biologic therapy. McGill University, Montreal, Quebec, Canada



Survival: 16.3 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
   
Drugs:
Country: Canada
   
City/State/Province: Montreal, Quebec
   
Hospital: McGill University
   
Journal: Link
   
Date: 8/2002

Description:
Patients: This Phase II study involved 22 patients with advanced renal cell carcinoma; 11 men and 11 women. Eighteen had undergone prior nephrectomy. Patients were divided into two groups Group 1 of 8 patients and Group 2 of 14 patients.

Treatment: The treatment for both groups consisted of a new angiogenesis inhibitor Neovastat. (Group 1 received the drug at a lower dose than Group 2.)

Toxicity: There was one grade 3 event, peripheral edema.

Results: For patients in Group 2 (the higher dose) the median survival was 16.3 months versus 7.1 months for the patients in Group 1.

Support: The study was sponsored by Les Laboratories Aeterna. Neovastat is manufactured by this company.

Correspondence: Dr. G. Batist

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