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Kidney Cancer treatment details. Biologic therapy. Immunotherapy. Wake Forest University, Winston-Salem, North Carolina, United States

Survival: 15.6 months
Toxicity Grade: 5
Treatments: Biologic therapy
Drugs: Thalomid
Country: United States
City/State/Province: Winston-Salem, North Carolina
Hospital: Wake Forest University
Journal: Link
Date: 6/2004

Patients: This Phase II trial involved 30 patients with metastatic renal cell carcinoma; 19 men and 11 women. The median age was 62. Seventeen patients had undergone a prior nephrectomy.

Treatment: The treatment consisted of a combination of interferon-alpha and thalidomide (thalomid).

Toxicity: One patient died during therapy of congestive heart failure and pulmonary edema. There was one grade 4 toxicity, gastrointestinal. Grade 3 toxicities included somnolence, neurosensory, central nervous system, pulmonary, gastrointestinal, anorexia, weakness, and rash.

Results: The median overall survival was 67.7 weeks (15.6 months).

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