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Kidney Cancer treatment details. Biologic therapy. University Medical Center, Nijmegen, Netherlands

Survival: 15.0 months
Toxicity Grade: 4
Treatments: Biologic therapy
Country: Netherlands
City/State/Province: Nijmegen
Hospital: University Medical Center
Journal: Link
Date: 3/2004

Patients: This Phase II trial involved 36 patients with advanced renal cell carcinoma, 24 men and 12 women. Twenty-two patients had undergone prior therapies. All patients had metastasis, most to the lungs and/or lymph nodes.

Treatment: The treatment consisted of administration of the chimeric monoclonal antibody G250.

Toxicity: Grade 4 toxicities included pulmonary, and hemorrhage. Grade 3 toxicities included pain, pulmonary, cardiovascular, neurology, hematologic, renal, and hepatic.

Results: The median survival was 15 months.

Support: The research was sponsored by Wilex AG. This company markets G250.

Correspondence: Dr. PFA Mulders

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