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Kidney Cancer treatment details. Chemotherapy. Immunotherapy. Institut Bergonie, Bordeaux, France

Survival: 14.0 months
Toxicity Grade: 3
Treatments: Chemotherapy
Drugs: Adrucil
Country: France
City/State/Province: Bordeaux
Hospital: Institut Bergonie
Journal: Link
Date: 12/2003

Patients: This Phase II study involved 35 patients with metastatic renal cell carcinoma; 27 men and 8 women. The median age was 62. All patients had received prior immunotherapy and their cancers had grown or spread during or after this treatment.

Treatment: The treatment consisted of subcutaneous interleukin-2 (IL-2), interferon alpha-2a (IFNalpha), the chemotherapy drug, 5-fluorouracil (5-FU, adrucil).

Toxicity: Grade 3 toxicities included fever, diarrhea, nausea/vomiting, skin disorders, hypotension, mucositis, cardiotoxicity, and hematological.

Results: The median survival for all patients was 14 months.

Correspondence: Dr. Alain Ravaud

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