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Kidney Cancer treatment details. Biologic therapy. Institut Gustave Roussy, Villejuif, France

Survival: 10.0 months
Toxicity Grade: 5
Treatments: Biologic therapy
Drugs: Thalomid
Country: France
City/State/Province: Villejuif
Hospital: Institut Gustave Roussy
Journal: Link
Date: 7/2002

Patients: This Phase II trial involved 40 patients with metastatic renal cell carcinoma; 32 men and 8 women. Previous treatments had included nephrectomy (32 patients), radiotherapy (15 patients), and immunotherapy (34 patients).

Treatment: The treatment consisted of administration of the drug, thalidomide.

Toxicity: There was one death from multiorgan failure, related to septic shock. The authors concluded that a connection with thalidomide treatment remains uncertain, it cannot be totally excluded. Grade 4 toxicities included: fatigue, lethargy, neuropathy, and thromboembolism.

Results: Median survival was 10 months.

Correspondence: Dr. B. Escudier

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