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Kidney Cancer treatment details. Chemotherapy. University of Chicago, Chicago, Illinois, United States

Survival: N/R
Toxicity Grade: 3
Treatments: Chemotherapy
Drugs: Temodar
Country: United States
City/State/Province: Chicago, Illinois
Hospital: University of Chicago
Journal: Link
Date: 8/2002

Patients: This Phase II trial involved 12 patients with metastatic renal cell carcinoma; seven men and 5 women. The median age was 59. Eight of the patients had undergone a prior nephrectomy.

Treatment: The treatment consisted of administration of a chemotherapy drug, temozolomide (temodar).

Toxicity: Grade three toxicities included hematologic (anemia), fatigue, nausea, and vomiting.

Results: There were no responses and the authors concluded that temozolomide was not active against renal cell carcinoma.

Support: The study was supported in part by Schering-Plough, Inc. This company markets temozolomide (temodar).

Correspondence: W.M. Stadler, MD

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