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Kidney Cancer treatment details. Chemotherapy. University of Chicago, Chicago, Illinois, United States

Survival: 10.0 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Adrucil
Country: United States
City/State/Province: Chicago, Illinois
Hospital: University of Chicago
Journal: Link
Date: 1/2002

Patients: This Phase II study involved 21 patients with metastatic renal cell carcinoma; 13 men and 8 women. The median age was 58 years. Twelve patients had undergone a prior nephrectomy and ten patients had undergone prior immunotherapy or chemotherapy.

Treatment: The treatment consisted of three chemotherapy drugs gemcitabine (gemzar), cisplatin (platinol), and fluorouracil (adrucil).

Toxicity: Nine patients came off the treatment due to toxicity. Grade 4 toxicities included neutropenia, pain, pulmonary, and hyperkalemia.

Results: There was one partial response and the median overall survival was 10 months.

Correspondence: C.M. George, MD

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