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Kidney Cancer treatment details. Biologic therapy. Chemotherapy. Immunotherapy. Wayne State University School of Medicine, Detroit, Michigan, United States



Survival: 9.5 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
Immunotherapy
   
Drugs: Taxol
Country: United States
   
City/State/Province: Detroit, Michigan
   
Hospital: Wayne State University School of Medicine
   
Journal: Link
   
Date: 8/2001

Description:
Patients: This Phase II study involved 21 patients with unresectable or metastatic renal cell carcinoma;16 men and 5 women. Prior therapies included nephrectomy (13 patients) and immunotherapy (11 patients).

Treatment: The treatment consisted of chemotherapy (paclitaxel (taxol)), immunotherapy (interferon-alpha), and biologic therapy (cis-retinoic acid).

Toxicity: Grade 4 toxicities included neutropenia and weight loss.

Results: The median survival was 9.5 months.

Support: The trial was supported in part by Bristol-Myers Squibb and Schering Pharmaceuticals. In addition, two of the four authors of the study received funding from one or both of these companies.

Correspondence: Ulka Vaishampayan, MD

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