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Brain Cancer treatment details. Chemotherapy. The Royal Marsden Hospital, Surrey, Surrey, United Kingdom



Survival: 5.4 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Temodar
Country: United Kingdom
   
City/State/Province: Surrey
   
Hospital: The Royal Marsden Hospital, Surrey
   
Journal: Link
   
Date: 1/2001

Description:
Patients: This Phase II study involved 126 patients with relapsed glioblastoma multiforme. (There were 12 other patients with different cancer types.)

Treatment: The treatment consisted of the chemotherapy drug, temozolomide (temodar).

Toxicity: Toxicities included grade 1-4 hematologic, asthenia, fatigue, fever, headache, confusion, convulsions, hemiparesis, paresis, anorexia, nausea, vomiting, and pulmonary infection.

Results: The median overall survival was 5.4 months.

Support: This study was supported in part by grants from Schering-Plough research institute. Schering-Plough manufactures temozolomide (temodar).

Correspondence: M. Brada, MD

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