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Breast Cancer treatment details. Biologic therapy. University of Erlangen-Nurnberg, Erlangen, Germany

Survival: N/R
Toxicity Grade: 3
Treatments: Biologic therapy
Country: Germany
City/State/Province: Erlangen
Hospital: University of Erlangen-Nurnberg
Journal: Link
Date: 12/2003

Patients: This Phase I trial involved 30 women with advanced breast cancer.

Treatment: The treatment consisted of the bispecific antibody MDX-H210 (anti-FcyR1 and anti-HER-2/neu).

Toxicity: Grade 3 toxicities included hepatic, respiratory, and nausea and vomiting. Other toxicities (less than grade 3) included chills, low-grade fever, and hypotension.

Results: No responses were seen and overall survival was not discussed.

Support: Medarex Inc. supported the trial. Medarex produced MDX-H210.

Correspondence: R. Repp, MD

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