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Brain Cancer treatment details. Chemotherapy. Johns Hopkins Oncology Center, Baltimore, Maryland , United States



Survival: 6.3 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Baltimore, Maryland
   
Hospital: Johns Hopkins Oncology Center
   
Journal: Link
   
Date: 7/2001

Description:
Patients: A total of 12 patients were enrolled onto this trial. Ten patients had glioblastoma multiforme.

Treatment: Treatment consisted of the drug, suramin. Suramin was originally used as treatment for African trypanosomiasis.

Toxicity: Three patients developed grade 3 to 4 neutropenia, constipation, diarrhea, or nausea.

Results: No partial or complete responses were seen in the 12-week point and, as a result, the study was closed early. Median survival was 191 days (6.3 months) from the time patients received their first suramin.

Correspondence: Stuart A. Grossman, MD

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