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Prostate Cancer treatment details. Chemotherapy. National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States



Survival: 14.7 months
   
Toxicity Grade: 3
   
Treatments: Chemotherapy
   
Drugs: Taxotere
Country: United States
   
City/State/Province: Bethesda, Maryland
   
Hospital: National Cancer Institute, National Institutes of Health
   
Journal: Link
   
Date: 7/2004

Description:
Patients: This Phase II trial involved a total of 75 patients with hormone refractory (androgen-independent) prostate cancer. Patients were divided into two groups: Group 1 comprised of 25 patients and Group 2 comprised of 50 patients. The median age for the patients in Group 1 was 67 years and the median baseline PSA was 64.4 (range .2 340.8).

Treatment: For patients in Group 1, the treatment consisted of the chemotherapy drug, docetaxel (taxotere).

Toxicity: For patients in Group 1, grade 3 toxicities included allergic reaction, diarrhea, constipation, pericardial effusion, muscular weakness, sensation disturbance, hyperglycemia, elevated total bilirubin, thrombocytopenia, and anemia.

Results: For patients in Group 1 the median survival was 14.7 months.

Correspondence: William D. Figg, MD

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