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Prostate Cancer treatment details. Chemotherapy. Taussig Cancer Center, The Cleveland Clinic Foundation, Cleveland, Ohio, United States



Survival: 16.7 months
   
Toxicity Grade: 3
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Cleveland, Ohio
   
Hospital: Taussig Cancer Center, The Cleveland Clinic Foundation
   
Journal: Link
   
Date: 1/2005

Description:
Patients: This Phase II study involved 39 patients with hormone refractory prostate cancer. The median age was 69 years and the median PSA was 117.7 (range 4.3 1497.8). Thirty-three patients had bone metastases and all patients had received prior hormone therapy.

Treatment: The treatment consisted of a new chemotherapy drug called satraplatin (JM-216).

Toxicity: Seventeen patients had a total of 35 hospitalizations. Twelve of these hospitalizations were believed to be related to JM-216. Grade 3 or higher toxicities included hematologic, diarrhea, vomiting, nausea, and elevated liver enzymes.

Results: The median survival was 16.7 months.

Correspondence: David Peereboom, MD

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