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Prostate Cancer treatment details. Chemotherapy. Leon Berard , Lyon, France



Survival: 9.4 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Eloxatin
Country: France
   
City/State/Province: Lyon
   
Hospital: Leon Berard
   
Journal: Link
   
Date: 8/2003

Description:
Patients: This Phase II randomized study involved 54 patients with hormone refractory metastatic prostate cancer. Patients were divided into two groups: Group 1 with 26 patients and Group 2 with 28 patients. For patients in Group 1, the median age was 68 and the median PSA was 85.

Treatment: For patients in Group 1, the treatment consisted of the chemotherapy drug oxaliplatin (eloxatin).

Toxicity: For patients in Group 1, grade 3-4 toxicities included anemia, neutropenia, asthenia, and neurosensory.

Results: For patients in Group 1, the median overall survival was 9.4 months.

Support: The study was supported by a grant from Sanofi-Synthelabo. This company manufactures oxaliplatin (eloxatin).

Correspondence: Dr. S. Mackenzie

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