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Prostate Cancer treatment details. Chemotherapy. Rudolfstiftung, Vienna, Austria



Survival: 10.1 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Emcyt
Country: Austria
   
City/State/Province: Vienna
   
Hospital: Rudolfstiftung
   
Journal: Link
   
Date: 1/2004

Description:
Patients: This Phase II study involved a total of 90 patients with hormone refractory prostate cancer. Patients were divided into two groups of 45 patients each: Group 1 and Group 2.

Treatment: For patients in Group 1 the treatment consisted of a combination of two chemotherapy drugs, estramustine (emcyt) and vinblastine (velban).

Toxicity: Two deaths “possibly related to treatment” occurred in this group. (One was from myocardial infarction and the other from cerebrovascular accident.) In addition, grade 3-4 toxicities included: diarrhea, nausea, neurological, bilirubin rise, and hematologic.

Results: Median survival was 44 weeks (10.1 months).

Correspondence: W. Albrecht, MD

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