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Brain Cancer treatment details. Chemotherapy. Radiation. University of Tubingen Medical School, Tubingen, Germany

Survival: 11.0 months
Toxicity Grade: 5
Treatments: Chemotherapy
Drugs: Gemzar
Country: Germany
City/State/Province: Tubingen
Hospital: University of Tubingen Medical School
Journal: Link
Date: 1/2001

Patients: Twenty-one patients with newly diagnosed glioblastoma were enrolled in this Phase II study.

Treatment: The treatment consisted of preirradiation chemotherapy gemcitabine (gemzar), followed by standard radiotherapy.

Toxicity: In the first cycle, three patients had grade 1 myelotoxicity, 2 had grade 2 myelotoxicity, and 2 had grade 3 myelotoxicity. In the second cycle, 5 patients had grade 1 myelotoxicity and 1 patient had a grade 2 myelotoxicity. One patient developed fatal bacterial pneumonia.

Results: The median overall survival was 11 months.

Support: The study was supported by Lilly. Eli Lilly markets Gemzar.

Correspondence: Michael Weller, MD

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