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Colon Cancer treatment details. Chemotherapy. National Cancer Institute, Bethesda, MD, United States



Survival: N/R
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Bethesda, MD
   
Hospital: National Cancer Institute
   
Journal: Link
   
Date: 5/2005

Description:
Patients: This phase I study involved 26 patients with advanced solid tissue cancers, including colorectal (6), ovarian (4), and breast (4). All patients had received treatment before the study, and twenty of the patients were 50 years of age or older.

Treatment: The treatment involved one chemotherapeutic agent: ixabepilone.

Toxicity: Grade 3-4 toxicities included: neutropenia, thrombocytopenia, and fatigue.

Results: No overall survival was determined and no responses were reported. The authors commented, "Prolonged disease stabilization was observed in patients with mesothelioma, ovarian carcinoma, and renal cell carcinoma."

Correspondence: Tito Fojo, M.D., Ph.D.

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