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Brain Cancer treatment details. Chemotherapy. UCLA School of Medicine, Los Angeles, California, United States



Survival: 5.6 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Camptosar
Country: United States
   
City/State/Province: Los Angeles, California
   
Hospital: UCLA School of Medicine
   
Journal: Link
   
Date: 5/2003

Description:
Patients: This study involved 14 patients with progressive or recurrent malignant gliomas. Twelve had glioblastoma multiforme and 2 had anaplastic astrocytoma.

Treatment: Treatment consisted of the chemotherapy drug, Irinotecan (Camptosar, CPT-11).

Toxicity: Primarily hematologic toxicity. Grade 3-4 neutropenia, nausea, and vomiting.

Results: Median survival for all patients was 24 weeks (5.6 months).

Support: The study was supported by a “grant-in-aid” from Pharmacia Corporation and two of the study’s authors are either employees or consultants of Pharmacia. Phamacia is involved in sale of CPT-11.

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