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Melanoma treatment details. Chemotherapy. Mayo Clinic, Rochester, MN, United States



Survival: 14.5 months
   
Toxicity Grade: 3
   
Treatments: Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Rochester, MN
   
Hospital: Mayo Clinic
   
Journal: Link
   
Date: 6/2005

Description:
Patients: This Phase II study involved 27 patients with metastatic malignant melanoma. Eighteen patients were men, and nine were women. The median age was 56. Metastatic sites included lymph nodes, liver, and lung.

Treatment: The treatment consisted of one chemotherapeutic agent: Bortezomib.

Toxicity: Grade 3 toxicities included sensory neuropathy, thrombocytopenia, constipation, fatigue, ileus, abdominal pain, and infection without neutropenia.

Results: The median overall survival was 14.5 months.
The authors however concluded, brotezomib "was not found to be effective in the treatment of patients with metastatic melanoma".

Correspondence: Svetomir N. Markovic, M.D.

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