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Ovarian Cancer treatment details. Chemotherapy. Sarah Cannon Cancer Center, Nashville, TN, United States



Survival: 24.0 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Paraplatin
Taxol
Vepesid
Country: United States
   
City/State/Province: Nashville, TN
   
Hospital: Sarah Cannon Cancer Center
   
Journal: Link
   
Date: 4/2005

Description:
Patients: This Phase II study involved 52 women with stage II or IV ovarian cancer. The median age was 57. None of the patients had received first-line chemotherapy before the study.

Treatment: The treatment consisted of three chemotherapeutic agents: paclitaxel, carboplatin, and etoposide.

Toxicity: Grade 3-4 toxicities included leukopenia, thrombocytopenia, peripheral neuropathy, arthralgia/myalgia, and fatigue.

Results: Although the overall median survival for the entire patient population was not determined, patients with suboptimal tumor debulking had a median survival of 24 months.

Support: Bristol-Myers Squibb provided financial support for this study. Bristol-Myers Squibb manufactures and markets paclitaxel, carboplatin, and etoposide.

Correspondence: John D. Hainsworth

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