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Ovarian Cancer treatment details. Chemotherapy. Cedars Sinai Medical Center, Los Angeles, CA, United States



Survival: 21.1 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Xeloda
Country: United States
   
City/State/Province: Los Angeles, CA
   
Hospital: Cedars Sinai Medical Center
   
Journal: Link
   
Date: 3/2005

Description:
Patients: This Phase II study involved 25 women with recurrent ovarian cancer. The median age was 61, and all patients had received at least one treatment before this study.

Treatment: The treatment consisted of one chemotherapeutic agent: capecitabine.

Toxicity: There was one treatment related death. Grade 3-4 toxicities included: GI toxicities, neutropenia, nausea/vomiting, sepsis, and dermatologic toxicities.

Results: Median survival was reported as "21.1+ months." The authors concluded, "capecitabine is associated with unacceptable toxicities (gastrointestinal, nausea/vomiting, and dermatological) at the approved dose of 2500 mg/m2/day and exhibits minimal activity in patients with platinum-sensitive ovarian cancer."

Correspondence: Agustin A. Garcia, MD

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