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Kidney Cancer treatment details. Biologic therapy. Karmanos Cancer Institute, Detroit, Michigan, United States



Survival: 10.0 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Detroit, Michigan
   
Hospital: Karmanos Cancer Institute
   
Journal: Link
   
Date: 3/2005

Description:
Patients: This Phase II study involved 19 patients with advanced renal carcinoma. 12 were men and 7 were women. The median age was 58. 17 patients had nephrectomies.

Treatment: The treatment consisted of fenretinide, which is a synthetic form of retinoid.

Toxicities: Grade 3 toxicities included thrombosis, fatigue, vomiting and diarrhea. Grade 2 toxicities included nyctalopia and visual toxicity.

Results: No objective responses were noted at the median survival was 10 months.

Correspondence: U. Vaishampayan, MD

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