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Liver Cancer treatment details. Biologic therapy. Radiation. Zhongshan Hospital, Fudan University, Shanghai, China



Survival: 10.0 months
   
Toxicity Grade:
   
Treatments: Biologic therapy
Radiation
   
Drugs:
Country: China
   
City/State/Province: Shanghai
   
Hospital: Zhongshan Hospital, Fudan University
   
Journal: Link
   
Date: 10/2004

Description:
Patients: This Phase I study involved a total of 37 patients with unresectable (inoperable) hepatocellular carcinoma. There were 28 men and 9 women and the average was 52.5 years.

Treatment: Treatment consisted of anti-HCC monoclonal antibody (131 I-Hepama-1 mAb) a radiolabeled monoclonal antibody.

Toxicity: Toxicity was not graded, but side effects included poor appetite, abdominal distention, abdominal pain, liver tenderness, jaundice, and hematologic toxicity.

Results: The median survival was 10 months for the 18 patients who had no evidence of metastases.

Correspondence: Shaoliang Chen, MD

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