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Liver Cancer treatment details. Biologic therapy. Santa Clara Valley Medical Center, San Jose, California, United States

Survival: 4.0 months
Toxicity Grade: 4
Treatments: Biologic therapy
Drugs: Thalomid
Country: United States
City/State/Province: San Jose, California
Hospital: Santa Clara Valley Medical Center
Journal: Link
Date: 1/2005

Patients: This Phase II study involved 27 patients with unresectable hepatocellular carcinoma, 21 men and 6 women. The median age was 62 years.

Treatment: Treatment consisted of one biological therapy - thalidomide. Thalidomide decreases the formation of new blood vessels.

Toxicity: Grade 3-4 toxicities included anemia, fatigue, somnolence, elevated enzymes, and elevated bilirubin.

Results: The median survival was 4 months.

Support: This study was supported in part by Celgene Inc. Celgene manufactures thalidomide.

Correspondence: Albert Lin, MD

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