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Lung Cancer treatment details. Chemotherapy. Radiation. Surgery. Washington University Medical Center, St. Louis, MO, United States

Survival: 56.3 months
Toxicity Grade: 5
Treatments: Chemotherapy
Drugs: Paraplatin
Country: United States
City/State/Province: St. Louis, MO
Hospital: Washington University Medical Center
Journal: Link
Date: 5/2005

Patients: This Phase II study involved 88 patients diagnosed with non-small-cell lung cancer (resected stage II or IIIA) Fifty-seven patients were men, and thirty-one were women. Forty-nine patients (56%) were younger than 60 years old.

Treatment: The treatment involved surgery and thoracic radiotherapy and chemotherapy with two drugs: paclitaxel and carboplatin.

Toxicity: There was one septic death. Grade 3-4 toxicities included granulocytopenia, leukopenia, thrombocytopenia, esophagitis, respiratory, and neurologic toxicity.

Results: The median overall survival was 56.3 months.

Support: Some authors have served as consultants, advisors or grant recipients to various pharmaceutical companies.

Correspondence: Jeffrey D. Bradley, M.D.

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