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Brain Cancer treatment details. Chemotherapy. Radiation. University of Vienna, Vienna, Austria

Survival: 14.5 months
Toxicity Grade: 5
Treatments: Chemotherapy
Drugs: DTIC-Dome
Country: Austria
City/State/Province: Vienna
Hospital: University of Vienna
Journal: Link
Date: 2/2003

Patients: This study involved 55 patients with newly diagnosed glioblastoma multiforme.

Treatment: The treatment consisted of two chemotherapy drugs - dacarbazine (DTIC-Dome) and fotemustine and radiation therapy.

Toxicity: The major toxicity was thrombocytopenia (grades 3 and 4). One patient died of septic fever during combined thrombocytopenia and leucopenia (grade 4) after the first dacarbazine and fotemustine administration. Other toxicities included erythordemia and alopecia.

Results: Median survival from time of neuropathologic diagnosis was 14.5 months.

Correspondence: Dr. B Fazeny-Dorner

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