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Ovarian Cancer treatment details. Biologic therapy. Christie Hospital NHS Trust, Manchester, United Kingdom



Survival: N/R
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
   
Drugs:
Country: United Kingdom
   
City/State/Province: Manchester
   
Hospital: Christie Hospital NHS Trust
   
Journal: Link
   
Date: 10/2003

Description:
Patients: This phase II study involved 11 women with recurrent epithelial ovarian cancer.

Treatment: The treatment consisted of a biological agent called bryoststin-1. Bryostatin-1 is a naturally occurring macrocyclic lactone with antineoplastic activity derived from the marine bryozoan, Bugula neritina.

Toxicity: Grade 3 toxicities included myalgia, fatigue, and vomiting.

Results: There were no responses and median survival was not reported.

Correspondence: Dr. A.R. Clamp

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