Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Colon Cancer treatment details. Biologic therapy. Chemotherapy. Surgery. University of Padova, Padova, Italy



Survival: 18.0 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
Surgery
   
Drugs: Platinol
Country: Italy
   
City/State/Province: Padova
   
Hospital: University of Padova
   
Journal: Link
   
Date: 6/2003

Description:
Patients: This Phase II study involved 46 patients treated for peritoneal carcinomatosis from colon adenocarcinoma.

Treatment: Thirty-four patients were treated with complete cytoreductive surgery immediately followed by intraoperative hyperthermic intraoperative intraperitoneal chemotherapy (HIIC) with mitomycin C and cisplatin.

Toxicity: Three patients had intra-abdominal complications (two abdominal abscesses and one hemoperitoneum), which required reoperation. Pleural effusion or pneumonia was recorded in four cases. According to the modified Ozolsí classification, grade I, II, III, and IV locoregional toxicity was observed in 18, 3, 1, and 1 patient, respectively. Hematological toxicity (grade I or II anemia, according to the World Health Organization classification) occurred in four cases.

Results: The median overall survival was 18 months.

Correspondence: Carlo Riccardo Rossi, MD

E-mail to a Friend Email Physician More Information